Sequence assembly is performed by the submitter, not by ENA curators (Figure 6). ENA sometimes receives the initial data as unassembled sequence reads, which are gradually complemented with additional layers of interpretation, such as assembly or annotation, by the author.
As a result, data is always changing. Sources of this change include:
- Assembly of sequence into larger fragments;
- Reducing the visibility of obsolete entries (once assembled);
- Sequence modifications;
- Daily updates;
- Corrections submitted by author.