Summary

  • InterPro is a resource for classifying proteins into families and predicting domains, repeats and functional sites.
  • InterPro integrates protein signatures from 11 member databases that are part of the InterPro consortium: PROSITE patterns, PROSITE profiles, PRINTS, ProDom, Pfam, SMART, TIGRFAMs, PIRSF, SUPERFAMILY, Gene3D and PANTHER. Protein signatures are predictive models based on similarities among proteins that have the same structure or function.
  • You can search InterPro with an amino acid sequence using the web site.
  • The InterPro web site can also be searched with a word or phrase, an entry ID, UniProtKB accessions and identifiers, GO terms and structural identifiers. 
  • Batches of sequences can be searched against InterPro by downloading the InterProScan tool, or using the EBI's web services.
  • The InterPro protein view provides a graphical representation of the signatures that match a particular protein, with information about protein family membership, sequence features, structural features, and structural predictions for that protein.    

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