Simply type in the protein, gene or chemical name of your molecule of interest, or a UniProtKB or ChEBI accession number, to see a binary view of all of the known interaction partners of that molecule. Drill down to see the details of any one piece of interaction evidence. View selected interactions in a simple graphical interface or export to Cytoscape at the click of a button. Advanced search options are available for more complex queries.
The IntAct project co-develops and supports the PSI-MI standard (see information box) and provides both a web service and a simple URL-based interface that allow direct computational access to retrieve interaction networks in PSI-MI format. Additionally, all files can be accessed and downloaded from the FTP site for local installation.