The European Genome-phenome Archive (EGA) provides a service for archiving, processing and disseminating all types of potentially identifiable genetic and phenotypic human data at EMBL-EBI. The EGA stores processed and raw data from many types of experiments including case control studies, cancer sequencing and population studies (7). Available data types include single nucleotide polymorphism (SNP) and copy number variation (CNV) genotypes, whole genome sequence and phenotype data. Each data type is stored at the EGA using methods designed to ensure that the storage and distribution is done in accordance with the consent and confidentiality agreements that the research participants agreed to at the time of entry into the study. Strict protocols govern how information is managed, stored and distributed by the EGA project.
You should use the EGA if you want to find genetic and phenotypic data resulting from biomedical research projects. EGA contains a large number of whole genome association studies. Access to these studies, which contain information on identifiable individuals, is controlled by a dataset access committee (DAC) and you need to obtain an account to gain access to these data. Finally, you can submit to the EGA to archive data on subjects who have consented to the use of their individual genetic data for biomedical research, but not for unlimited public data release (Figure 1.5).
Figure 1.5 The EGA contains exclusive data collected from individuals whose consent agreements authorize data release only for specific research use.