Variation consequences continued

This presentation tells you about some of the more detailed information you can get about variation consequences.

Exercise 4b

• Retrieve all coding TranscriptVariationAlleles for transcript ENST00000001008 in human and get for each TVA:
  • Allele string
  • Codon change
  • Amino acid change
  • SIFT and PolyPhen predictions*
    
    *if information is available
    
    Hint: We are only interested in information for the alternate allele. You need to fetch TranscriptVariation objects first.

Anja explains the answers to these questions in this 2-minute video. You can also download her sample script and expected output.