Linking Open Data in Biology using Ontologies and Literature Mining
The Semantic Web offers a vision of a data centric infrastructure which enables integration, analysis and reuse of the wealth of data that exists both now and in the future. To make this 'web of data' a reality, it is necessary to have these vast volumes of data use a standardised format and explicit descriptions such that the data can be unambiguously understood and exchanged. Ontologies described in the Web Ontology Language (OWL) provide a formal, standardised representation of the data and the relationships between this data and offer a mechanism by which data integration exchange can occur. Connecting these description with the openly available data on the web is termed "Linked Open Data". Linked Open Data has become important to the biomedical community where the quantities of open data available have become so large that computational methods of integration and analysis are necessary to enable cross-domain sharing and integration and novel insights to continue. In the tutorial you will learn about Semantic Web technology for the integration of biological data from different data resources including the scientific literature. We will examine the role of ontologies in the Linked Open Data vision and those widely used in the bioinformatics community and will illustrate how the use of biomedical ontologies can have practical applications in the linked data vision of the Semantic Web.
| Time | Topic |
|---|---|
| Day 1 (Thursday – May 19th, 2011) | |
| 09:00 - 12:30 | Session 1: The concept of the Semantic Web |
| 09:00 - 10:30 | Definitions of Semantic Web, overview on component, technologies, data integration in the Semantic Web (Malone / Rebholz-Schuhmann) |
| 10:30 - 11:00 | Coffee/Tea |
| 11:00 - 12:30 | Controlled Vocabularies, Taxonomies, Ontologies, use of the semantic resources for categorisation of data and literature analysis (Rebholz-Schuhmann) |
| 12:30 - 13:30 | Lunch |
| 13:30 - 15:00 | Session 2: Representation of data on the Semantic Web |
| 13:30 - 14:15 | Role of ontologies for describing data and introduction to the Web Ontology Language (OWL) (Malone) |
| 14:15 - 15:00 | Approaches to linking data and ontologies with RDF including current tools. Explanation of technical implementations and benefits (Rebholz-Schuhmann) |
| 15:00 - 15:30 | Coffee/Tea |
| 15:30 - 16:30 |
Principles of OWL based bio-ontologies in the community (Malone) |
| 16:30 - 17:00 |
Closing discussion |
| Day 2 (Friday – May 20th, 2011) | |
| 09:00 - 12:30 | Session 3: Advanced features of the Semantic Web |
| 09:00 - 10:30 | Advanced features of OWL description logic reasoners detecting errors defined classes and building complex hierarchies (Malone / Stevens) |
| 10:30 - 11:00 | Coffee/Tea |
| 11:00 - 12:30 | Extraction of features and facts from the literature, integration into the Linked Data (Rebholz-Schuhmann) |
| 12:30 - 13:30 | Lunch |
| 13:30 - 15:00 | Session 4: Of data and Semantic Web |
| 13:30 - 15:00 | Linked Open Data and biomedical data resources, examples of existing solutions, querying across data resources (Malone (Atlas) / Rebholz-Schuhmann (SESL) / Le Novere (MIRIAM) ) |
| 15:00 - 15:30 | Coffee/Tea |
| 15:30 - 16:00 | Knowledge discovery from the Literature and in the Linked Data cloud: cross-comparison of data and validation, hypothesis generation (Rebholz-Schuhmann) |
| 16:00 - 16:30 | Future of Semantic Web in Biomedicine (Malone / Rebholz-Schumann) |
| 16:30 - 17:00 | Closing |
Once you have completed the course, please take some time to complete the course feedback form by following this link:
All of the course presentations and materials are enclosed in the following links:
/training/sites/ebi.ac.uk.training/files/materials/2011/110519_ontologies/slides.zip
/training/sites/ebi.ac.uk.training/files/materials/2011/110519_ontologies/rds-slides.zip
/training/sites/ebi.ac.uk.training/files/materials/2011/110519_ontologies/owl_files.zip
/training/sites/ebi.ac.uk.training/files/materials/2011/110519_ontologies/misc.zip
