Joint EMBL-EBI-Wellcome Trust Course: Resources for Computational Drug Discovery
This joint EBI-Wellcome Trust course aims to provide participants with the principles of computational chemical biology and how to use computational methods to probe, explore and modulate biological systems using chemical tools. The course will be comprised of a mixture of lectures and hands-on exercises. The conceptual framework will be covered along with direct practical experience of retrieving and analysing chemogenomics data. Participants will be able to do their own target analysis and identify appropriate chemical tools for probing biological systems of personal interest.
Target audience
The interdisciplinary and interactive programme is ideal for both academics and industrial researchers interested in drug discovery; or for researchers looking to progress from basic functional genomics towards translational research. The course will be highly interactive and will include problem solving sessions each day. Attendees are strongly encouraged to bring ideas of work to be addressed during these sessions. Places on this course are limited and will be awarded on merit of applications received.
Participants should have a degree in a biomedical discipline. No previous training in bioinformatics is required; but attendees should be comfortable with computers and Internet searching.
Learning objectives
The overall aim of the course is to provide:
- Knowledge of the content of publicly available bioactivity databases their use in identifying and selection of bioactive molecules for screening
- Knowledge and hand-on experience of computational chemistry and biology tools that can help in compound design and target evaluation
- Experience of using these tools for analysis of compounds and targets of personal interest
Sessions
• Concepts of computational drug discovery
• Publicly available databases and bioactivity resources
• Compound design and virtual screening to expand bioactive chemical space
• Selecting compounds to screen against novel targets and for target validation
• Strategies for drug re-use and repositioning
• Identification of off-target effects by cross-reactivity analysis
• Target analysis and use of genomic data for drug discovery
Draft programme to follow shortly.
Applications:
Please note: Places on this course are limited to 30 and will be awarded on merit. Applicants will be required to complete an online application form when registering.
You will be asked to complete the following information:
- Qualifications & Justification for attendance
- Any relevant publications
- A scientific outline of your current research project
- Details of your supervisor. Your supervisor will then receive an e-mail requesting a supporting statement to complete your application.
Registrations cannot be accepted without the supervisors supporting statement.Please notify your supervisor that they will receive an e-mail from the Wellcome Trust asking them to complete your application which includes submitting a supporting statement.
Applicationdeadline: 8 October 2013
Further details regarding the course and how to apply can be found here:https://registration.hinxton.wellcome.ac.uk/display_info.asp?id=386
Fees:
The course is subsidised by the Wellcome Trust Scientific Conferences and there is a registration fee of£600, which includes registration, meals and accommodation for the nights of the 9, 10, 11 and 12 December 2013. If you require additional nights this will be at an additional cost, please contact the Wellcome Trust conference centre,reception@wtconference.org.uk directly for availability.
EBI Industry Membersare eligible for a reduced registration fee of£400, which includes registration, meals and accommodation for the nights of the 9,10, 11 and 12 December 2013.
Bursaries are available for this event, we ask that you complete the registration process, and email lucy.criddle@wtgc.org directly to confirm that you wish to apply for a registration (including meals and accommodation) bursary. The individual will need to cover all travel costs.
The selection process will take place in October 2013. Those selected will be required to make the registration payment in full.
Travel Visas
If you require a letter of acceptance in order to obtain a travel Visa please e-mail lucy.criddle@wtgc.org
Lucy Criddle
Wellcome Trust Scientific Conferences
Wellcome Trust Genome Campus
Hinxton
Cambridge
CB10 1RQ
lucy.criddle@wtgc.org