Gua-Cys distribution

Hydrogen bonds

Number of Gua sidechains in dataset 32250 ( 3.8% )

Number of Cys sidechains in dataset 9033 ( 1.1% )

Total number of Gua-Cys contacts 48

3D distribution.
Histograms:

Inter-planar angle (IPA).

* Non-random at 95.0% confidence level.
** Non-random at 97.5% confidence level.
*** Non-random at 99.0% confidence level.
**** Non-random at 99.5% confidence level.

Packing geometries

The significance of any clustering in the contacts is assessed with reference to packing-geometries generated at random from 100 trials of 48 randomly-chosen and randomly placed contacts.

Random packing geometry:

Here there are no clusters, so no valid statistics on the clustering in this distribution can be derived. However, the clusters found can be taken to be significant.

View cluster(s) in RasMol

Display mode: Rasmol script, or standard RasMol.
Show: All sidechains, cluster representative only, or both.

Colour sidechains by: cluster, or atom colour.

The clusters

The pairs of plots below show a representative sidechain for each cluster.

In the first plot of each pair the sidechains are shown as ball-and-stick models; in the second plot the van der Waals surfaces are superimposed as wire-cage contours. The reference sidechain is shown in purple while the cluster representative is shown in orange. Click on the first plot to get a magnified view, including the other cluster members.

Each cluster representative is chosen to have a r.m.s.d. of <1.5 Angstroms from all other members of the cluster. The standard deviation shows how significant the clustering is, when compared with a randomly-generated contact distribution for these two sidechains.

The ticks on the back walls in the plots correspond to distances of 1 Angstrom.