MCSG Pre-deposition functional
analysis server

The aim of this MCSG server is to provide early analysis of near complete structures in order to identify any interesting features prior to deposition. This server will utilise all of the methods in the public ProFunc server but will be flagged as a priority structure for manual examination. A report will be written and any interesting or unusual features identified to the authors.

As with the public server some methods take minutes to run whereas others take hours. You will be notified by e-mail when the entire process is complete, but can check on preliminary results as they become available.

From this page you can submit your own structure, or retrieve the results of a previously submitted run.

Choose option A or B:

   A   
 
 
Upload PDB-format file:  
  or
   B   
 
Go to previous analysis   Id no.:  Security code:

References:
  • Laskowski R A, Watson J D, Thornton J M (2005). ProFunc: a server for predicting protein function from 3D structure. Nucleic Acids Res., 33, W89-W93. [Abstract] [HTML] [PDF]
  • Laskowski R A, Watson J D, Thornton J M (2005). Protein function prediction using local 3D templates. J. Mol. Biol., 351, 614-626.

    • Notes:
  • Although this is a pre-deposition server, please rename any non-standard amino acids (eg selenomethionines, phosphotyrosines, etc) to their standard equivalents before submitting the structure to ProFunc. This will increase the chances of ProFunc finding matches to both sequence and structure templates. (For selenomethionines identified by residue name MSE there is no need to make any changes).

    • ProFunc documentation
    		E-mail to:- Roman Laskowski roman@ebi.ac.uk