Pattern PS00383
TYR_PHOSPHATASE_1
[LIVMF]-H-C-x(2)-G-x(2)-R-[STC]-[STAGP]
The following PDB entries contain known "true positive" matches for this PROSITE pattern, or matches that are highly likely to be correct.
1 | 26 | 51

.PDB..Code
Title
1bzc  Human ptp1b catalytic domain complexed with tpi
1bzh  Cyclic peptide inhibitor of human ptp1b
1bzj  Human ptp1b complexed with tpicooh
1c83  Crystal structure of protein tyrosine phosphatase 1b complexed with 6- (oxalyl- amino)- 1h- indole- 5- carboxylic acid
1c84  Crystal structure of protein tyrosine phosphatase 1b complexed with 3- (oxalyl- amino)- naphthalene- 2- carboxlic acid
1c85  Crystal structure of protein tyrosine phosphatase 1b complexed with 2- (oxalyl- amino)- benzoic acid
1c86  Crystal structure of protein tyrosine phosphatase 1b (r47v, d48n) complexed with 2- (oxalyl- amino- 4,7- dihydro- 5h- thieno[2,3- c]pyran- 3- carboxylic acid
1c87  Crystal structure of protein tyrosine phosphatase 1b complexed with 2- (oxalyl- amino- 4,7- dihydro- 5h- thieno[2,3- c]pyran- 3- carboxylic acid
1c88  Crystal structure of protein tyrosine phosphatase 1b complexed with 2- (oxalyl- amino)- 4,5,6,7- tetrahydro- thieno[2,3- c]pyridine- 3- carboxylic acid
1ecv  Crystal structure of protein tyrosine phosphatase 1b complexed with 5- iodo- 2- (oxalyl- amino)- benzoic acid
1g7f  Human ptp1b catalytic domain complexed with pnu177496
1g7g  Human ptp1b catalytic domain complexes with pnu179326
1gfy  Residue 259 is a key determinant of substrate specificity of protein- tyrosine phosphatase 1b and alpha
1jf7  Human ptp1b catalytic domain complexed with pnu177836
1kak  Human tyrosine phosphatase 1b complexed with an inhibitor
1kav  Human tyrosine phosphatase 1b complexed with an inhibitor
1l8g  Crystal structure of ptp1b complexed with 7- (1,1- dioxo- 1h- benzo[d]isothiazol- 3- yloxymethyl)- 2- (oxalyl- amino)- 4,7- dihydro- 5h- thieno[2,3- c]pyran- 3- carboxylic acid
1lqf  Structure of ptp1b in complex with a peptidic bisphosphonate inhibitor
1n6w  Crystal structure of protein tyrosine phosphatase 1b with potent and selective bidentate inhibitor compound 2
1nl9  Potent, selective protein tyrosine phosphatase 1b inhibitor compound 12 using a linked- fragment strategy
1nny  Potent, selective protein tyrosine phosphatase 1b inhibitor compound 23 using a linked- fragment strategy
1no6  Potent, selective protein tyrosine phosphatase 1b inhibitor compound 5 using a linked- fragment strategy
1nwe  Ptp1b r47c modified at c47 with n- [4- (2- {2- [3- (2- bromo- acetylamino)- propionylamino]- 3- hydroxy- propionylamino}- ethyl)- phenyl]- oxalamic acid
1nwl  Crystal structure of the ptp1b complexed with sp7343- sp7964, a ptyr mimetic
1nz7  Potent, selective inhibitors of protein tyrosine phosphatase 1b using a second phosphotyrosine binding site, complexed with compound 19.