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PDBsum entry 2w49

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protein metals Protein-protein interface(s) links
Contractile protein PDB id
2w49
Jmol
Contents
Protein chains
159 a.a. *
90 a.a. *
141 a.a. *
277 a.a. *
39 a.a. *
(+ 10 more) 372 a.a. *
Metals
_CA ×16
* Residue conservation analysis
PDB id:
2w49
Name: Contractile protein
Title: Isometrically contracting insect asynchronous flight muscle
Structure: Troponin c, skeletal muscle. Chain: 0, 3, 6, 9. Fragment: residues 5-163. Synonym: tnnc2. Troponin t, fast skeletal muscle isoforms. Chain: 1, 4, 7, y. Fragment: residues 148-237. Synonym: tnnt3. Troponin i, fast skeletal muscle.
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Tissue: skeletal muscle. Oryctolagus cuniculus. Rabbit. Organism_taxid: 9986. Tissue: skeletal muscle
Authors: S.Wu,J.Liu,M.C.Reedy,R.T.Tregear,H.Winkler, C.Franzini-Armstrong,H.Sasaki,C.Lucaveche,Y.E.Goldman, M.K.Reedy,K.A.Taylor
Key ref: S.Wu et al. (2010). Electron tomography of cryofixed, isometrically contracting insect flight muscle reveals novel actin-myosin interactions. PLoS One, 5, 12643. PubMed id: 20844746
Date:
24-Nov-08     Release date:   05-May-10    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P02588  (TNNC2_CHICK) -  Troponin C, skeletal muscle
Seq:
Struc:
163 a.a.
159 a.a.
Protein chains
Pfam   ArchSchema ?
P12620  (TNNT3_CHICK) -  Troponin T, fast skeletal muscle isoforms
Seq:
Struc:
263 a.a.
90 a.a.
Protein chains
Pfam   ArchSchema ?
P68246  (TNNI2_CHICK) -  Troponin I, fast skeletal muscle
Seq:
Struc:
183 a.a.
141 a.a.*
Protein chains
Pfam   ArchSchema ?
P58772  (TPM1_RABIT) -  Tropomyosin alpha-1 chain
Seq:
Struc:
284 a.a.
277 a.a.
Protein chains
Pfam   ArchSchema ?
P58772  (TPM1_RABIT) -  Tropomyosin alpha-1 chain
Seq:
Struc:
284 a.a.
39 a.a.
Protein chains
Pfam   ArchSchema ?
P68135  (ACTS_RABIT) -  Actin, alpha skeletal muscle
Seq:
Struc:
377 a.a.
372 a.a.
Key:    PfamA domain  PfamB domain  Secondary structure
* PDB and UniProt seqs differ at 3 residue positions (black crosses)

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytoplasm   6 terms 
  Biological process     regulation of muscle contraction   5 terms 
  Biochemical function     nucleotide binding     8 terms  

 

 
PLoS One 5:12643 (2010)
PubMed id: 20844746  
 
 
Electron tomography of cryofixed, isometrically contracting insect flight muscle reveals novel actin-myosin interactions.
S.Wu, J.Liu, M.C.Reedy, R.T.Tregear, H.Winkler, C.Franzini-Armstrong, H.Sasaki, C.Lucaveche, Y.E.Goldman, M.K.Reedy, K.A.Taylor.
 
  ABSTRACT  
 
No abstract given.