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SAS results for UniProt accession no. P10175

Sequence annotated by structure

Key:
Sec. struc: By homology
  Helix Strand  
Residue contacts:   to ligand
Active sites:   (from PDB SITE records)

Secondary structure shown in red comes from a homologous protein structure which is at least 30% sequence identical to the target protein and has an alignment overlap of at least 80 residues or at least three-quarters of the length of the target sequence (whichever overlap is the larger).

Click on annotated residues to get source(s) of each annotation.

 

FASTA alignment for UniProt accession no. P10175 - coloured by no. of contacts to ligand

Below are the FASTA results from a search of the sequence of UniProt accession no. P10175 against all protein sequences in the PDB. Identical sequences are grouped together and represented by a single 'consensus' sequence (asterisked) onto which all relevant annotations are mapped. The number of sequences represented by each consensus sequence is shown by the '×n' on the right of the alignment. Use the box below to modify the annotations shown on the alignment. At the bottom of the page are given the FASTA stats for all the sequences. There you can exclude any sequences from the alignment.

Struct

FASTA

The search returned 23 unique sequences (including 1 consensus sequences) giving 48 sequence matches in all. The 3 sequences excluded from the alignment are listed at the end.

Modify alignment: Annotate by:
  Number:  
  Show secondary structure: Yes No  


                1         2         3         4         5         6     
       12345678901234567890123456789012345678901234567890123456789012345    Protein name
       ---------+---------+---------+---------+---------+---------+-----    ------------
P10175 -----------------------------------------------------------------    Cytochrome c oxidase subunit 8B, mitochondrial OS=Bos  ...
1occ:M*-----------------------------------------------------------------×26 Structure of bovine heart cytochromE C oxidase at the fully  ...
3sjp:A -----------------------------------------------------------------    Structural characterization of a gii.4 2004 norovirus varian
2vge:A -----------------------------------------------------------------    Crystal structure of thE C-terminal region of human iaspp
3skb:I -----------------------------------------------------------------    Structural characterization of a gii.4 2004 norovirus varian
1zjj:A -----------------------------------------------------------------    Crystal structure of hypothetical protein ph1952 from  ...
3sej:I -----------------------------------------------------------------    Structural characterization of a gii.4 2004 norovirus  ...
3sld:H -----------------------------------------------------------------    Structural characterization of a gii.4 2004 norovirus  ...
3sln:H -----------------------------------------------------------------    Structural characterization of a gii.4 2004 norovirus  ...
3l81:A -----------------------------------------------------------------    Crystal structure of adaptor protein complex 4 (ap-4) mu4  ...
4n2r:A -----------------------------------------------------------------    Crystal structure of the alpha-l-arabinofuranosidase  ...
4n1i:A -----------------------------------------------------------------    Crystal structure of the alpha-l-arabinofuranosidase  ...
2c3a:B -----------------------------------------------------------------    Structure of unliganded hsv gd reveals a mechanism for  ...
1hk6:A -----------------------------------------------------------------    Ral binding domain from sec5
2bl0:A -----------------------------------------------------------------    Physarum polycephalum myosin ii regulatory domain
3cyj:A -----------------------------------------------------------------    Crystal structure of a mandelate racemase/muconate  ...
3cbg:A -----------------------------------------------------------------    Functional and structural characterization of a  ...
3rcn:A -----------------------------------------------------------------    Crystal structure of beta-n-acetylhexosaminidase from  ...
1uad:C -----------------------------------------------------------------    Crystal structure of the rala-gppnhp-sec5 ral-binding  ...
2r0p:A -mnapietdvlilgggpvgmalaldlahrqvghlvveqtdgtithprvgtigprsmelfrrwgva    K252c-soaked rebc
4eiq:A napietdvlilgggpvgmalaldlahrqvghlvvdagdithpkvstigprsmelfrrwgvakqir    Chromopyrrolic acid-soaked rebc-10x with bound 7-carboxy-k25

                                         1         1         1         1
           7         8         9         0         1         2         3
       67890123456789012345678901234567890123456789012345678901234567890    Protein name
       ----+---------+---------+---------+---------+---------+---------+    ------------
P10175 -----------------------------------------------------------------    Cytochrome c oxidase subunit 8B, mitochondrial OS=Bos  ...
1occ:M*-----------------------------------------------------------------×26 Structure of bovine heart cytochromE C oxidase at the fully  ...
3sjp:A -----------------------------------------------------------------    Structural characterization of a gii.4 2004 norovirus varian
2vge:A -----------------------------------------------------------------    Crystal structure of thE C-terminal region of human iaspp
3skb:I -----------------------------------------------------------------    Structural characterization of a gii.4 2004 norovirus varian
1zjj:A -----------------------------------------------------------------    Crystal structure of hypothetical protein ph1952 from  ...
3sej:I -----------------------------------------------------------------    Structural characterization of a gii.4 2004 norovirus  ...
3sld:H -----------------------------------------------------------------    Structural characterization of a gii.4 2004 norovirus  ...
3sln:H -----------------------------------------------------------------    Structural characterization of a gii.4 2004 norovirus  ...
3l81:A ------------------------------------------------------------nevfl    Crystal structure of adaptor protein complex 4 (ap-4) mu4  ...
4n2r:A -----------------------------------------------------------------    Crystal structure of the alpha-l-arabinofuranosidase  ...
4n1i:A -----------------------------------------------------------------    Crystal structure of the alpha-l-arabinofuranosidase  ...
2c3a:B --------------------------------------lpvldqltdppgvrrcyhiqaglpdpf    Structure of unliganded hsv gd reveals a mechanism for  ...
1hk6:A -----------------------------------------------------------------    Ral binding domain from sec5
2bl0:A -----------------------------------------------------------------    Physarum polycephalum myosin ii regulatory domain
3cyj:A -----------------------------------------------------------------    Crystal structure of a mandelate racemase/muconate  ...
3cbg:A -----------------------------------------------------------------    Functional and structural characterization of a  ...
3rcn:A -----------------------------------------------------------------    Crystal structure of beta-n-acetylhexosaminidase from  ...
1uad:C -----------------------------------------------------------------    Crystal structure of the rala-gppnhp-sec5 ral-binding  ...
2r0p:A kqirtagwpgdhpldaawvtrvgghevyriplgtadtratpehtpepdaicpqhwlapllaeavg    K252c-soaked rebc
4eiq:A tagwpgdhpldaawvtrvgghevyriplgtadtratpehtpepdaicpahwlapllaeavgerlr    Chromopyrrolic acid-soaked rebc-10x with bound 7-carboxy-k25

                1         1         1         1         1         1     
                4         5         6         7         8         9     
       12345678901234567890123456789012345678901234567890123456789012345    Protein name
       ---------+---------+---------+---------+---------+---------+-----    ------------
P10175 -----------------------------------------------------------------    Cytochrome c oxidase subunit 8B, mitochondrial OS=Bos  ...
1occ:M*-----------------------------------------------------------------×26 Structure of bovine heart cytochromE C oxidase at the fully  ...
3sjp:A ----------------esrtkpftvpiltveemtnsrfpipleklftgpssafvvqpqngrcttd    Structural characterization of a gii.4 2004 norovirus varian
2vge:A -----------------------------------------------------------------    Crystal structure of thE C-terminal region of human iaspp
3skb:I ----------------------rtkpftvpiltveemtnsrfpipleklftgpssafvvqpqngr    Structural characterization of a gii.4 2004 norovirus varian
1zjj:A -----------------------------------------------------------------    Crystal structure of hypothetical protein ph1952 from  ...
3sej:I -----------------------------esrtkpftvpiltveemtnsrfpipleklftgpssa    Structural characterization of a gii.4 2004 norovirus  ...
3sld:H ---------------------esrtkpftvpiltveemtnsrfpipleklftgpssafvvqpqng    Structural characterization of a gii.4 2004 norovirus  ...
3sln:H ----------------------esrtkpftvpiltveemtnsrfpipleklftgpssafvvqpqn    Structural characterization of a gii.4 2004 norovirus  ...
3l81:A dvverlsvliasngsllkvdvqgeirlksflpsgsemriglteefsvgkselrgygpgirvdevs    Crystal structure of adaptor protein complex 4 (ap-4) mu4  ...
4n2r:A -----------------------------------------------------------------    Crystal structure of the alpha-l-arabinofuranosidase  ...
4n1i:A -----------------------------------------------------------------    Crystal structure of the alpha-l-arabinofuranosidase  ...
2c3a:B qppslpitvyyavleracrsvllnapseapqivrgasedvrkqpynltiawfrmggncaipitvm    Structure of unliganded hsv gd reveals a mechanism for  ...
1hk6:A -----------------------------------------------------------------    Ral binding domain from sec5
2bl0:A -----------------------------------------------------------------    Physarum polycephalum myosin ii regulatory domain
3cyj:A -------------------------------------------prverlevsaytvptdypesdg    Crystal structure of a mandelate racemase/muconate  ...
3cbg:A ---------------------------------------------------------------kg    Functional and structural characterization of a  ...
3rcn:A -----------------------------------------------------------------    Crystal structure of beta-n-acetylhexosaminidase from  ...
1uad:C -----------------------------------------------------------------    Crystal structure of the rala-gppnhp-sec5 ral-binding  ...
2r0p:A erlrtrsrldsfeqrddhvratitdlrtgatravharylvacdgassptrkalgidapprhrtqv    K252c-soaked rebc
4eiq:A trsrldsfeqrddhvratitdlrtgatravharylvacdgassptrkalgidapprhrtqvfrni    Chromopyrrolic acid-soaked rebc-10x with bound 7-carboxy-k25

           2         2         2         2         2         2         2
           0         1         2         3         4         5         6
       67890123456789012345678901234567890123456789012345678901234567890    Protein name
       ----+---------+---------+---------+---------+---------+---------+    ------------
P10175 -----------------------------------------------------------------    Cytochrome c oxidase subunit 8B, mitochondrial OS=Bos  ...
1occ:M*-----------------------------------------------------------------×26 Structure of bovine heart cytochromE C oxidase at the fully  ...
3sjp:A gallgttqlspvdictfrgdvthiagtqnytmnlasqnwnnydpteeipaplgtpdfvgkiqgvl    Structural characterization of a gii.4 2004 norovirus varian
2vge:A -----------------------------------------------------------------    Crystal structure of thE C-terminal region of human iaspp
3skb:I cttdgallgttqlspvdictfrgdvthiagtqnytmnlasqnwnnydpteeipaplgtpdfvgki    Structural characterization of a gii.4 2004 norovirus varian
1zjj:A -----------------------------------------------------------------    Crystal structure of hypothetical protein ph1952 from  ...
3sej:I fvvqpqngrcttdgallgttqlspvdictfrgdvthiagtqnytmnlsqnwnnydpteeipaplg    Structural characterization of a gii.4 2004 norovirus  ...
3sld:H rcttdgallgttqlspvdictfrgdvthiagtqnytmnlasqnwnnydpteeipaplgtpdfvgk    Structural characterization of a gii.4 2004 norovirus  ...
3sln:H grcttdgallgttqlspvdictfrgdvthiagtqnytmnlasqnwnnydpteeipaplgtpdfvg    Structural characterization of a gii.4 2004 norovirus  ...
3l81:A fhssvnldefeshrilrlqppqgeltvmryqlsddlpsplpfrlfpsvqwdrgsgrlqvylklrc    Crystal structure of adaptor protein complex 4 (ap-4) mu4  ...
4n2r:A ----------------scalpttyrwtssaplaqpkdgwvslkdfthvpyngqhlvyasyhdstk    Crystal structure of the alpha-l-arabinofuranosidase  ...
4n1i:A ----------------scalpttyrwtssaplaqpkdgwvslkdfthvpyngqhlvyasyhdstk    Crystal structure of the alpha-l-arabinofuranosidase  ...
2c3a:B eytecsynkslgacpirtqprwnyydsfsavsednlgflmhapafetagtylrlvkindwteitq    Structure of unliganded hsv gd reveals a mechanism for  ...
1hk6:A -----------------------------------------------------------------    Ral binding domain from sec5
2bl0:A -----------------------------------------------------------------    Physarum polycephalum myosin ii regulatory domain
3cyj:A tlqwdsttmilveahgggrkglgytygdvsvgrfvesklagvaegsdalsppavwarmqaairna    Crystal structure of a mandelate racemase/muconate  ...
3cbg:A itgfdpslysylqsisaddsfylaqlrretahlpgapmqispeqaqflgllisltgakqvleigv    Functional and structural characterization of a  ...
3rcn:A ---------msafhqlipapwsfsagtgeleldagtsvgadpelrgprrwltralggatgwdlap    Crystal structure of beta-n-acetylhexosaminidase from  ...
1uad:C -----------------------------------------------------------------    Crystal structure of the rala-gppnhp-sec5 ral-binding  ...
2r0p:A frnilfrapelrsllgeraalffflmllrfplraldgrglyrltvgvdtmdsfelvrravafdte    K252c-soaked rebc
4eiq:A lfrapelrsllgeraalvfflmlssslrfplrsldgrglynlvvgvddamdsfelvrravafdte    Chromopyrrolic acid-soaked rebc-10x with bound 7-carboxy-k25

                2         2         2         3         3         3     
                7         8         9         0         1         2     
       12345678901234567890123456789012345678901234567890123456789012345    Protein name
       ---------+---------+---------+---------+---------+---------+-----    ------------
P10175 ---------------------------------------------mlrlap-tvrllqapl---r    Cytochrome c oxidase subunit 8B, mitochondrial OS=Bos  ...
1occ:M*-----------------------------------------------------------------×26 Structure of bovine heart cytochromE C oxidase at the fully  ...
3sjp:A tqttrrdgstrghkatvstgsvhftpklgsvqfstdtsndfetgqntrftp--vgvvq-pq---q    Structural characterization of a gii.4 2004 norovirus varian
2vge:A ---------------------------------------sprkarrarlnp-lvllldaal---t    Crystal structure of thE C-terminal region of human iaspp
3skb:I qgvltqttrrdgstrghkatvstgsvhftpklgsvqfstdtsndfetgqnt-rftpvgvvp---q    Structural characterization of a gii.4 2004 norovirus varian
1zjj:A -------------------------------mvaiifdmdgvlyrgnraip-gvreliefl---k    Crystal structure of hypothetical protein ph1952 from  ...
3sej:I tpdfvgkiqgvltqttrrdgstrghkatvstgsvhftpklgsvqfstfetg-qntrftpvg---v    Structural characterization of a gii.4 2004 norovirus  ...
3sld:H iqgvltqttrrdgstrghkatvstgsvhftpklgsvqfstdtdfetgqntr-ftpvgvvep---q    Structural characterization of a gii.4 2004 norovirus  ...
3sln:H kiqgvltqttrrdgstrghkatvstgsvhftpklgsvqfstdtfetgqntr-ftpvgvvep---q    Structural characterization of a gii.4 2004 norovirus  ...
3l81:A dllsksqalnvrlhlplprgvvslsqelsspeqkaelaegalrwdlprvqg-gsqlsglfq---m    Crystal structure of adaptor protein complex 4 (ap-4) mu4  ...
4n2r:A ygsmafspfkhwadmatatqtgmtqaavaptvfyftpkklwflvsqwgsapftyrtstdpt---k    Crystal structure of the alpha-l-arabinofuranosidase  ...
4n1i:A ygsmafspfkhwadmatatqtgmtqaavaptvfyftpkklwflvsqwgsapftyrtstdpt---k    Crystal structure of the alpha-l-arabinofuranosidase  ...
2c3a:B filehrakgsckyalplrippsaclspqayqqgvtvdsigmlprfipenqr-tvavyslki---a    Structure of unliganded hsv gd reveals a mechanism for  ...
1hk6:A ---------------------------------------------hmrqpp-lvtgi-spn---e    Ral binding domain from sec5
2bl0:A ----------------------------------------------rrige-ivkvvqaaa---r    Physarum polycephalum myosin ii regulatory domain
3cyj:A grpgvgamavsavdialwdlkarllglpladalprfhaevpvygsggftsy-plrrlqeql---g    Crystal structure of a mandelate racemase/muconate  ...
3cbg:A frgysalamalqlppdgqiiacdqdpnataiakkywqkagvaekislrlgp-alatleqlt---q    Functional and structural characterization of a  ...
3rcn:A apareagirllldpsldaeayrlevsdavvisaggaagafygaqtllqllg-paalrqapvvave    Crystal structure of beta-n-acetylhexosaminidase from  ...
1uad:C ----------------------------------------------srqpp-lvtgi-spn---e    Crystal structure of the rala-gppnhp-sec5 ral-binding  ...
2r0p:A ievlsdsewhlthrvadsfsagrvfltgdaahtlspsggfgmntgigsaad-lgwklaatl---r    K252c-soaked rebc
4eiq:A ievlsdsewhlthrvadsfsagrvfltgdaahtlspsggfgmntgigsaad-lgwklaatl---r    Chromopyrrolic acid-soaked rebc-10x with bound 7-carboxy-k25

           3         3         3         3         3         3         3
           3         4         5         6         7         8         9
       67890123456789012345678901234567890123456789012345678901234567890    Protein name
       ----+---------+---------+---------+---------+---------+---------+    ------------
P10175 --gwa---vp--k-----ah-itak--paktp---tspk--eq--ai--------gls-v-tf--    Cytochrome c oxidase subunit 8B, mitochondrial OS=Bos  ...
1occ:M*---------------------ITAK--PAKTP---TSPK--EQ--AI--------GLS-V-TF--×26 Structure of bovine heart cytochromE C oxidase at the fully  ...
3sjp:A ---wv---lp--dysgrdshnvhla--pavap---tfpg--eq--ll--------ffr-s-tm--    Structural characterization of a gii.4 2004 norovirus varian
2vge:A --g-e---le--v-----vq-qavk--emndp---sqpn--ee--gitalhnaicgan-y-si--    Crystal structure of thE C-terminal region of human iaspp
3skb:I --qwv---lp--dysgrdshnvhla--pavap---tfpg--eq--ll--------ffr-s-tmpn    Structural characterization of a gii.4 2004 norovirus varian
1zjj:A --erg---ip--f-----af-ltnn--stktp---emyr--ekllkm--------gid-v-ss--    Crystal structure of hypothetical protein ph1952 from  ...
3sej:I --qwv---lp--dysgrdshnvhla--pavap---tfpg--eq--ll--------ffr-s-tmpg    Structural characterization of a gii.4 2004 norovirus  ...
3sld:H --qwv---lp--dysgrdshnvhla--pavap---tfpg--eq--ll--------ffr-s-tmpm    Structural characterization of a gii.4 2004 norovirus  ...
3sln:H --qwv---lp--dysgrdshnvhla--pavap---tfpg--eq--ll--------ffr-s-tmpm    Structural characterization of a gii.4 2004 norovirus  ...
3l81:A --dvp---gp--p-----gl-glgp--aslsf---elpr--ht--cs--------glq-v-rf--    Crystal structure of adaptor protein complex 4 (ap-4) mu4  ...
4n2r:A vngws---ap--q-----pl-ftgk--vadsg---tgpi--dq--tv--------iad-d-rk--    Crystal structure of the alpha-l-arabinofuranosidase  ...
4n1i:A vngws---ap--q-----pl-ftgk--vadsg---tgpi--dq--tv--------iad-d-rk--    Crystal structure of the alpha-l-arabinofuranosidase  ...
2c3a:B --gwh---gp--k-----ap-ytstllppelp---edpe--ds--al--------ledpv-gt--    Structure of unliganded hsv gd reveals a mechanism for  ...
1hk6:A --g-----ip--w-----tk-vtir--genlg---tgpt--dl---i--------glt-i-cg--    Ral binding domain from sec5
2bl0:A --gw----ve--r-----kh-frqa--reksv---sa-----r--ii--------qdn-iray--    Physarum polycephalum myosin ii regulatory domain
3cyj:A --gwaaagiprvk-----mk-vgre--pekdp---ervraare--ai--------ges-v-el--    Crystal structure of a mandelate racemase/muconate  ...
3cbg:A --gkp---lp--e-----fd-lifi--dadkr---nypr--yy--ei--------gln-l-lr--    Functional and structural characterization of a  ...
3rcn:A --gws---vp--r-----vs-vedk--prfgy---rgtm--ld--va--------rhf-m-pk--    Crystal structure of beta-n-acetylhexosaminidase from  ...
1uad:C --g-----ip--w-----tk-vtir--genlg---tgpt--dl---i--------glt-i-cg--    Crystal structure of the rala-gppnhp-sec5 ral-binding  ...
2r0p:A --gwa---gp--g-----ll-atye--eerrpvaitsle--ea--nv--------nlr-r-t---    K252c-soaked rebc
4eiq:A --gwa---gp--g-----ll-atye--eerrpvaitsle--ea--nv--------nlr-r-t---    Chromopyrrolic acid-soaked rebc-10x with bound 7-carboxy-k25

                4         4         4         4         4         4     
                0         1         2         3         4         5     
       12345678901234567890123456789012345678901234567890123456789012345    Protein name
       ---------+---------+---------+---------+---------+---------+-----    ------------
P10175 -lsf--llpagwv--ly---hldnykkssaa----------------------------------    Cytochrome c oxidase subunit 8B, mitochondrial OS=Bos  ...
1occ:M*-LSF--LLPAGWV--LY---HLDNYKKS-------------------------------------×26 Structure of bovine heart cytochromE C oxidase at the fully  ...
3sjp:A -mnldcllpqewv---q---hf--yqesapaqsdvallrfvnpdtgrvlfecklhksgyvtvaht    Structural characterization of a gii.4 2004 norovirus varian
2vge:A -vdf--litagan--vn---spdshgwtplhcaascndtvicmalvqhgaaifattlsdgatafe    Crystal structure of thE C-terminal region of human iaspp
3skb:I -ldc--llpqewv---q---hf--yqesapaqsdvallrfvnpdtgrvlfecklhksgyvtvaht    Structural characterization of a gii.4 2004 norovirus varian
1zjj:A --si--iitsglatrlymskhldpgkifviggeglvkemqalgwgivtldearqgswkevkhvvv    Crystal structure of hypothetical protein ph1952 from  ...
3sej:I nldc--llpqewv---q---hf--yqesapaqsdvallrfvnpdtgrvlfecklhksgyvtvaht    Structural characterization of a gii.4 2004 norovirus  ...
3sld:H nldc--llpqewv---q---hf--yqesapaqsdvallrfvnpdtgrvlfecklhksgyvtvaht    Structural characterization of a gii.4 2004 norovirus  ...
3sln:H nldc--llpqewv---q---hf--yqesapaqsdvallrfvnpdtgrvlfecklhksgyvtvaht    Structural characterization of a gii.4 2004 norovirus  ...
3l81:A -lrl--afphkwvrhls---hsdayviri------------------------------------    Crystal structure of adaptor protein complex 4 (ap-4) mu4  ...
4n2r:A -vyl--ffvadng--kv---yrtsmaigdfpanfgtasevilsdtqaklfeavqvytvagqnqyl    Crystal structure of the alpha-l-arabinofuranosidase  ...
4n1i:A -vyl--ffvadng--kv---yrtsmaigdfpanfgtasevilsdtqaklfeavqvytvagqnqyl    Crystal structure of the alpha-l-arabinofuranosidase  ...
2c3a:B -vap--qippnwh--ip---siqdcatpyh-----------------------------------    Structure of unliganded hsv gd reveals a mechanism for  ...
1hk6:A -hnc--lltaewm--sa---skivcrvgqakndkgdiivttksggkgtstvsfkllkpek-----    Ral binding domain from sec5
2bl0:A -lef--knwawwk--lf---akarpllv-------------------------------------    Physarum polycephalum myosin ii regulatory domain
3cyj:A -mvd--angaytr--kq---alywagafareagisyleepvssedreglrllrdrgpggvaiaag    Crystal structure of a mandelate racemase/muconate  ...
3cbg:A -rgg--lmvidnv--lw---hgkvtevdpqeaqtqvlqqfnrdlaqdervrisviplgdgmtlal    Functional and structural characterization of a  ...
3rcn:A -dnv--lrfievm--am---hklnvlhlhltddqgwrmqinrypkltetgawrresslgswragv    Crystal structure of beta-n-acetylhexosaminidase from  ...
1uad:C -hnc--lltaewm--sa---skivcrvgqakndkgdiivttksggrgtstvsfkllkp-------    Crystal structure of the rala-gppnhp-sec5 ral-binding  ...
2r0p:A -mdr--elppglh--dd---gprgeriraavaeklersgarrefdapgihfghtyrssivcgewr    K252c-soaked rebc
4eiq:A -mdr--elppglh--dd---gprgeriraavaeklersgarrefdapgihfghtyrssivcgepw    Chromopyrrolic acid-soaked rebc-10x with bound 7-carboxy-k25

           4         4         4         4         5         5         5
           6         7         8         9         0         1         2
       67890123456789012345678901234567890123456789012345678901234567890    Protein name
       ----+---------+---------+---------+---------+---------+---------+    ------------
P10175 -----------------------------------------------------------------    Cytochrome c oxidase subunit 8B, mitochondrial OS=Bos  ...
1occ:M*-----------------------------------------------------------------×26 Structure of bovine heart cytochromE C oxidase at the fully  ...
3sjp:A gqhdlvippngyfrfdswvnqfytlapmg------------------------------------    Structural characterization of a gii.4 2004 norovirus varian
2vge:A kcdpyregyadcatyladveqsmglmnsgavyalwdysaefgdelsfregesvtvlrrdgpeetd    Crystal structure of thE C-terminal region of human iaspp
3skb:I gqhdlvippngyfrfdswvnqfytlapmg------------------------------------    Structural characterization of a gii.4 2004 norovirus varian
1zjj:A gldpdltyeklkyatlairngatfigtnpdatlpgeegiypgagsiiaalkvatnvepiiigkpn    Crystal structure of hypothetical protein ph1952 from  ...
3sej:I gqhdlvippngyfrfdswvnqfytlapm-------------------------------------    Structural characterization of a gii.4 2004 norovirus  ...
3sld:H gqhdlvippngyfrfdswvnqfytlapmg------------------------------------    Structural characterization of a gii.4 2004 norovirus  ...
3sln:H gqhdlvippngyfrfdswvnqfytlapmg------------------------------------    Structural characterization of a gii.4 2004 norovirus  ...
3l81:A -----------------------------------------------------------------    Crystal structure of adaptor protein complex 4 (ap-4) mu4  ...
4n2r:A miveaqgtngryfrsftansldgewkvqagsesapfagkansgaswtndvshgdlirsnpdqtmt    Crystal structure of the alpha-l-arabinofuranosidase  ...
4n1i:A miveaqgtngryfrsftansldgewkvqagsesapfagkansgaswtndvshgdlirsnpdqtmt    Crystal structure of the alpha-l-arabinofuranosidase  ...
2c3a:B -----------------------------------------------------------------    Structure of unliganded hsv gd reveals a mechanism for  ...
1hk6:A -----------------------------------------------------------------    Ral binding domain from sec5
2bl0:A -----------------------------------------------------------------    Physarum polycephalum myosin ii regulatory domain
3cyj:A eyewtlpqlhdlagcvdilqadvtrcggitgllrvdgicrghqipfsahcapavsahaccavesl    Crystal structure of a mandelate racemase/muconate  ...
3cbg:A kk---------------------------------------------------------------    Functional and structural characterization of a  ...
3rcn:A fdgrphggfytqddlreivafaadrhitvipeidvpghsqaaiaaypelgagpspvevwtrwgin    Crystal structure of beta-n-acetylhexosaminidase from  ...
1uad:C -----------------------------------------------------------------    Crystal structure of the rala-gppnhp-sec5 ral-binding  ...
2r0p:A psarpgaraphawltpttstldlfgrgfvllsfgttdgveavtrafadrhvpletvtchapeiha    K252c-soaked rebc
4eiq:A rpsarpgaraphawltpttstldlfgrgfvllsfgttdgveavtrafadrhvpletvtchapeih    Chromopyrrolic acid-soaked rebc-10x with bound 7-carboxy-k25

                5         5         5         5         5         5     
                3         4         5         6         7         8     
       12345678901234567890123456789012345678901234567890123456789012345    Protein name
       ---------+---------+---------+---------+---------+---------+-----    ------------
P10175 -----------------------------------------------------------------    Cytochrome c oxidase subunit 8B, mitochondrial OS=Bos  ...
1occ:M*-----------------------------------------------------------------×26 Structure of bovine heart cytochromE C oxidase at the fully  ...
3sjp:A -----------------------------------------------------------------    Structural characterization of a gii.4 2004 norovirus varian
2vge:A wwwaalhgqegyvprnyfglfprvkp---------------------------------------    Crystal structure of thE C-terminal region of human iaspp
3skb:I -----------------------------------------------------------------    Structural characterization of a gii.4 2004 norovirus varian
1zjj:A epmyevvremfpgeelwmvgdrldtdiafakkfgmkaimvltgvssledikkseykpdlvlpsvy    Crystal structure of hypothetical protein ph1952 from  ...
3sej:I -----------------------------------------------------------------    Structural characterization of a gii.4 2004 norovirus  ...
3sld:H -----------------------------------------------------------------    Structural characterization of a gii.4 2004 norovirus  ...
3sln:H -----------------------------------------------------------------    Structural characterization of a gii.4 2004 norovirus  ...
3l81:A -----------------------------------------------------------------    Crystal structure of adaptor protein complex 4 (ap-4) mu4  ...
4n2r:A idpcrlqllyqgrdknkvpssydlapyrpglltlyglgle-------------------------    Crystal structure of the alpha-l-arabinofuranosidase  ...
4n1i:A idpcrlqllyqgrdknkvpssydlapyrpglltlyglgleqklise-------------------    Crystal structure of the alpha-l-arabinofuranosidase  ...
2c3a:B -----------------------------------------------------------------    Structure of unliganded hsv gd reveals a mechanism for  ...
1hk6:A -----------------------------------------------------------------    Ral binding domain from sec5
2bl0:A -----------------------------------------------------------------    Physarum polycephalum myosin ii regulatory domain
3cyj:A lhleyfhdharverllfdgtldpeggslrpdpdrpglglelkrseagkyaa--------------    Crystal structure of a mandelate racemase/muconate  ...
3cbg:A -----------------------------------------------------------------    Functional and structural characterization of a  ...
3rcn:A etvlevsetslefyrnvldevveifpspwislggdevpltqwqasaqaqakaaelglddvsglhs    Crystal structure of beta-n-acetylhexosaminidase from  ...
1uad:C -----------------------------------------------------------------    Crystal structure of the rala-gppnhp-sec5 ral-binding  ...
2r0p:A lyerahvlvrpdghvawrgdhlpaelgglvdkvrgaa----------------------------    K252c-soaked rebc
4eiq:A alyerahvlvrpdghvawrgdhlpaelgglvdkvrgaa---------------------------    Chromopyrrolic acid-soaked rebc-10x with bound 7-carboxy-k25

           5         6         6         6         6         6         6
           9         0         1         2         3         4         5
       67890123456789012345678901234567890123456789012345678901234567890    Protein name
       ----+---------+---------+---------+---------+---------+---------+    ------------
P10175 -----------------------------------------------------------------    Cytochrome c oxidase subunit 8B, mitochondrial OS=Bos  ...
1occ:M*-----------------------------------------------------------------×26 Structure of bovine heart cytochromE C oxidase at the fully  ...
3sjp:A -----------------------------------------------------------------    Structural characterization of a gii.4 2004 norovirus varian
2vge:A -----------------------------------------------------------------    Crystal structure of thE C-terminal region of human iaspp
3skb:I -----------------------------------------------------------------    Structural characterization of a gii.4 2004 norovirus varian
1zjj:A elidylk----------------------------------------------------------    Crystal structure of hypothetical protein ph1952 from  ...
3sej:I -----------------------------------------------------------------    Structural characterization of a gii.4 2004 norovirus  ...
3sld:H -----------------------------------------------------------------    Structural characterization of a gii.4 2004 norovirus  ...
3sln:H -----------------------------------------------------------------    Structural characterization of a gii.4 2004 norovirus  ...
3l81:A -----------------------------------------------------------------    Crystal structure of adaptor protein complex 4 (ap-4) mu4  ...
4n2r:A -----------------------------------------------------------------    Crystal structure of the alpha-l-arabinofuranosidase  ...
4n1i:A -----------------------------------------------------------------    Crystal structure of the alpha-l-arabinofuranosidase  ...
2c3a:B -----------------------------------------------------------------    Structure of unliganded hsv gd reveals a mechanism for  ...
1hk6:A -----------------------------------------------------------------    Ral binding domain from sec5
2bl0:A -----------------------------------------------------------------    Physarum polycephalum myosin ii regulatory domain
3cyj:A -----------------------------------------------------------------    Crystal structure of a mandelate racemase/muconate  ...
3cbg:A -----------------------------------------------------------------    Functional and structural characterization of a  ...
3rcn:A wfvgqlalhlkhhgratsvwdelpdgalvaswrgyeggidalrkgydvvmcpehklyldhrqadg    Crystal structure of beta-n-acetylhexosaminidase from  ...
1uad:C -----------------------------------------------------------------    Crystal structure of the rala-gppnhp-sec5 ral-binding  ...
2r0p:A -----------------------------------------------------------------    K252c-soaked rebc
4eiq:A -----------------------------------------------------------------    Chromopyrrolic acid-soaked rebc-10x with bound 7-carboxy-k25

                6         6         6         6         7         7     
                6         7         8         9         0         1     
       12345678901234567890123456789012345678901234567890123456789012345    Protein name
       ---------+---------+---------+---------+---------+---------+-----    ------------
P10175 -----------------------------------------------------------------    Cytochrome c oxidase subunit 8B, mitochondrial OS=Bos  ...
1occ:M*-----------------------------------------------------------------×26 Structure of bovine heart cytochromE C oxidase at the fully  ...
3sjp:A -----------------------------------------------------------------    Structural characterization of a gii.4 2004 norovirus varian
2vge:A -----------------------------------------------------------------    Crystal structure of thE C-terminal region of human iaspp
3skb:I -----------------------------------------------------------------    Structural characterization of a gii.4 2004 norovirus varian
1zjj:A -----------------------------------------------------------------    Crystal structure of hypothetical protein ph1952 from  ...
3sej:I -----------------------------------------------------------------    Structural characterization of a gii.4 2004 norovirus  ...
3sld:H -----------------------------------------------------------------    Structural characterization of a gii.4 2004 norovirus  ...
3sln:H -----------------------------------------------------------------    Structural characterization of a gii.4 2004 norovirus  ...
3l81:A -----------------------------------------------------------------    Crystal structure of adaptor protein complex 4 (ap-4) mu4  ...
4n2r:A -----------------------------------------------------------------    Crystal structure of the alpha-l-arabinofuranosidase  ...
4n1i:A -----------------------------------------------------------------    Crystal structure of the alpha-l-arabinofuranosidase  ...
2c3a:B -----------------------------------------------------------------    Structure of unliganded hsv gd reveals a mechanism for  ...
1hk6:A -----------------------------------------------------------------    Ral binding domain from sec5
2bl0:A -----------------------------------------------------------------    Physarum polycephalum myosin ii regulatory domain
3cyj:A -----------------------------------------------------------------    Crystal structure of a mandelate racemase/muconate  ...
3cbg:A -----------------------------------------------------------------    Functional and structural characterization of a  ...
3rcn:A ddepvpvgfvttlqavyefeplpgtdfpgrllgaqaniwsehldsprrvqfaafprlsaisevfw    Crystal structure of beta-n-acetylhexosaminidase from  ...
1uad:C -----------------------------------------------------------------    Crystal structure of the rala-gppnhp-sec5 ral-binding  ...
2r0p:A -----------------------------------------------------------------    K252c-soaked rebc
4eiq:A -----------------------------------------------------------------    Chromopyrrolic acid-soaked rebc-10x with bound 7-carboxy-k25

           7         7         7         7         7         7  
           2         3         4         5         6         7  
       678901234567890123456789012345678901234567890123456789012            Protein name
       ----+---------+---------+---------+---------+---------+--            ------------
P10175 ---------------------------------------------------------            Cytochrome c oxidase subunit 8B, mitochondrial OS=Bos  ...
1occ:M*---------------------------------------------------------        ×26 Structure of bovine heart cytochromE C oxidase at the fully  ...
3sjp:A ---------------------------------------------------------            Structural characterization of a gii.4 2004 norovirus varian
2vge:A ---------------------------------------------------------            Crystal structure of thE C-terminal region of human iaspp
3skb:I ---------------------------------------------------------            Structural characterization of a gii.4 2004 norovirus varian
1zjj:A ---------------------------------------------------------            Crystal structure of hypothetical protein ph1952 from  ...
3sej:I ---------------------------------------------------------            Structural characterization of a gii.4 2004 norovirus  ...
3sld:H ---------------------------------------------------------            Structural characterization of a gii.4 2004 norovirus  ...
3sln:H ---------------------------------------------------------            Structural characterization of a gii.4 2004 norovirus  ...
3l81:A ---------------------------------------------------------            Crystal structure of adaptor protein complex 4 (ap-4) mu4  ...
4n2r:A ---------------------------------------------------------            Crystal structure of the alpha-l-arabinofuranosidase  ...
4n1i:A ---------------------------------------------------------            Crystal structure of the alpha-l-arabinofuranosidase  ...
2c3a:B ---------------------------------------------------------            Structure of unliganded hsv gd reveals a mechanism for  ...
1hk6:A ---------------------------------------------------------            Ral binding domain from sec5
2bl0:A ---------------------------------------------------------            Physarum polycephalum myosin ii regulatory domain
3cyj:A ---------------------------------------------------------            Crystal structure of a mandelate racemase/muconate  ...
3cbg:A ---------------------------------------------------------            Functional and structural characterization of a  ...
3rcn:A snpagrdydefltrltgahlarleamgveyrplsgpapwqqrpgvegwkrdydaeql            Crystal structure of beta-n-acetylhexosaminidase from  ...
1uad:C ---------------------------------------------------------            Crystal structure of the rala-gppnhp-sec5 ral-binding  ...
2r0p:A ---------------------------------------------------------            K252c-soaked rebc
4eiq:A ---------------------------------------------------------            Chromopyrrolic acid-soaked rebc-10x with bound 7-carboxy-k25

Residue colours: black = 0, purple = 1, blue = 2, green = 3, orange = 4, red = 5 or more contacts.

Sequence listing

The listing below shows the FASTA statistics for the PDB entries that matched UniProt accession no. P10175. Ditto marks indicate identical sequences represented by a single representative sequence in the alignment above. The representative is asterisked and the names of all its duplicate sequences are indented to the right.

Structures whose names are given in purple are those that are annotated above. The parameters defining which sequences can transfer their annotations are shown at the bottom of the page where they can be altered and the alignment regenerated.

Use the checkboxes to the left of the PDB codes to exclude any sequences from the alignment (or to add back any sequences in the Excluded list). Then click the SELECT button at the bottom of the page to redisplay the alignment.

Aligned sequences

  Smith-
Waterman
score
%-tage
identity
a.a.
overlap
Seq
len
z-score E-
value
  PDB
code
Protein name
1. - - - 70 - - P10175 Cytochrome c oxidase subunit 8B, mitochondrial OS=Bos taurus GN=COX8B PE=1 SV=3
2. 281 100.0% 43 43 438.8 1.8e-17 1occ:M * Structure of bovine heart cytochromE C oxidase at the fully oxidized state
3. " " " " " "  = 1oco:M *
Bovine heart cytochromE C oxidase in carbon monoxide-bound state
4. " " " " " "  = 1ocr:M *
Bovine heart cytochromE C oxidase in the fully reduced state
5. " " " " " "  = 1ocz:M *
Bovine heart cytochromE C oxidase in azide-bound state
6. " " " " " "  = 1v54:M *
Bovine heart cytochromE C oxidase at the fully oxidized stat
7. " " " " " "  = 1v55:M *
Bovine heart cytochromE C oxidase at the fully reduced state
8. " " " " " "  = 2dyr:M *
Bovine heart cytochromE C oxidase at the fully oxidized stat
9. " " " " " "  = 2dys:M *
Bovine heart cytochromE C oxidase modified by dccd
10. " " " " " "  = 2eij:M *
Bovine heart cytochromE C oxidase in the fully reduced state
11. " " " " " "  = 2eik:M *
Cadmium ion binding structure of bovine heart cytochromE C o the fully reduced state
12. " " " " " "  = 2eil:M *
Cadmium ion binding structure of bovine heart cytochromE C o the fully oxidized state
13. " " " " " "  = 2eim:M *
Zinc ion binding structure of bovine heart cytochromE C oxid fully reduced state
14. " " " " " "  = 2ein:M *
Zinc ion binding structure of bovine heart cytochromE C oxidase in the fully oxidized state
15. " " " " " "  = 2occ:M *
Bovine heart cytochromE C oxidase at the fully oxidized stat
16. " " " " " "  = 2y69:M *
Bovine heart cytochromE C oxidase re-refined with molecular oxygen
17. " " " " " "  = 2ybb:X *
Fitted model for bovine mitochondrial supercomplex i1iii2iv single particle cryo-em (emd-1876)
18. " " " " " "  = 2zxw:M *
Bovine heart cytochromE C oxidase at the fully oxidized stat ray exposure dataset)
19. " " " " " "  = 3abk:M *
Bovine heart cytochromE C oxidase at the no-bound fully redu (50k)
20. " " " " " "  = 3abl:M *
Bovine heart cytochromE C oxidase at the fully oxidized state (15-s x-ray exposure dataset)
21. " " " " " "  = 3abm:M *
Bovine heart cytochromE C oxidase at the fully oxidized state (200-s x-ray exposure dataset)
22. " " " " " "  = 3ag1:M *
Bovine heart cytochromE C oxidase in the carbon monoxide-bou reduced state at 280 k
23. " " " " " "  = 3ag2:M *
Bovine heart cytochromE C oxidase in the carbon monoxide-bou reduced state at 100 k
24. " " " " " "  = 3ag3:M *
Bovine heart cytochromE C oxidase in the nitric oxide-bound reduced state at 100 k
25. " " " " " "  = 3ag4:M *
Bovine heart cytochromE C oxidase in the cyanide ion-bound f reduced state at 100 k
26. " " " " " "  = 3asn:M *
Bovine heart cytochromE C oxidase in the fully oxidized stat at 1.7470 angstrom wavelength
27. " " " " " "  = 3aso:M *
Bovine heart cytochromE C oxidase in the fully oxidized stat at 0.9 angstrom wavelength
28. 81 32.9% 76 294 125.4 5.2 3sjp:A Structural characterization of a gii.4 2004 norovirus varian
29. 78 31.1% 61 208 123.4 6.7 2vge:A Crystal structure of thE C-terminal region of human iaspp
30. 77 34.4% 61 291 119.5 11 3skb:I Structural characterization of a gii.4 2004 norovirus varian
31. 76 32.9% 70 261 118.8 12 1zjj:A Crystal structure of hypothetical protein ph1952 from pyroco horikoshii ot3
32. 75 33.9% 62 284 116.7 16 3sej:I Structural characterization of a gii.4 2004 norovirus varian bound to secretor lewis hbga (leb)
33. 75 33.9% 62 293 116.5 16 3sld:H Structural characterization of a gii.4 2004 norovirus varian bound to a trisaccharide
34. 75 33.9% 62 292 116.5 16 3sln:H Structural characterization of a gii.4 2004 norovirus varian bound to h pentasaccharide
35. 74 41.9% 31 250 116.1 17 3l81:A Crystal structure of adaptor protein complex 4 (ap-4) mu4 su terminal domain, in complex with a sorting peptide from the precursor protein (app)
36. 74 35.0% 40 306 114.7 21 4n2r:A Crystal structure of the alpha-l-arabinofuranosidase umabf62 ustilago maydis in complex with l-arabinofuranose
37. 74 35.0% 40 312 114.5 21 4n1i:A Crystal structure of the alpha-l-arabinofuranosidase umabf62 ustilago maidys
38. 73 28.3% 53 274 114.0 23 2c3a:B Structure of unliganded hsv gd reveals a mechanism for receptor-mediated activation of virus entry
39. 67 28.6% 56 95 112.6 27 1hk6:A Ral binding domain from sec5
40. 65 27.6% 58 63 112.5 27 2bl0:A Physarum polycephalum myosin ii regulatory domain
41. 73 35.4% 48 359 112.0 29 3cyj:A Crystal structure of a mandelate racemase/muconate lactonizi like protein from rubrobacter xylanophilus
42. 70 27.1% 59 218 111.1 33 3cbg:A Functional and structural characterization of a cationdependent o-methyltransferase from the cyanobacterium synechocystis sp. Strain pcc 6803
43. 74 37.5% 32 525 110.8 34 3rcn:A Crystal structure of beta-n-acetylhexosaminidase from arthro aurescens
44. 64 29.1% 55 92 108.3 47 1uad:C Crystal structure of the rala-gppnhp-sec5 ral-binding domain complex
45. 72 37.5% 48 512 108.0 49 2r0p:A K252c-soaked rebc
46. 72 37.5% 48 514 108.0 49 4eiq:A Chromopyrrolic acid-soaked rebc-10x with bound 7-carboxy-k25

Number of sequences: 46

Excluded sequences

  Smith-
Waterman
score
%-tage
identity
a.a.
overlap
Seq
len
z-score E-
value
  PDB
code
Protein name
1. 72 37.5% 48 522 107.9 50 2r0g:A Chromopyrrolic acid-soaked rebc with bound 7-carboxy-k252c
2. 72 37.5% 48 516 107.9 49 3ept:A Structure of the rebeccamycin biosynthetic enzyme rebc with reduced flavin
3. 72 37.5% 48 521 107.9 49 4eip:A Native and k252c bound rebc-10x

Number of sequences: 3

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Annotation parameters

The parameters below were used in determining which structural annotations could be transferred on to the target sequence. You can change the parameters and regenerate the SAS alignments and annotation by pressing the Rerun button.

Min. seq. identity:   Min. seq. overlap   Max. E-value

  spacer

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