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2c4l

Structure Title:  Structure of neuraminidase subtype n9 complexed with 30 mm sialic acid (nana, neu5ac), crystal soaked for 24 hours at 291 k and finally backsoaked for 30 min in a cryoprotectant solution which did not contain neu5ac
Structure Header:  Hydrolase
Associated ECs:  3.2.1.18 [S]

Chains:
Code   Molecule
1.   A   Neuraminidase subtype n9,  current chain [S]
2. A   Neuraminidase subtype n9
3. A   Neuraminidase subtype n9
4. A   Neuraminidase subtype n9

Change domain classification: CATH | SCOP | Pfam


Domain Family Family Name Ligand
bound by
> 1 domain
PDB Ligand (code residue chain, name) Cognate Ligand Similarity
1. Neur [S] Neuraminidase N SIA 1469 A, O-sialic acid  [C][S] N-Acetylneuraminate  [R][S][L] 1
N SIA 1470 A, O-sialic acid  [C][S] N-Acetylneuraminate  [R][S][L] 1
Y NAG 1471 A, N-acetyl-d-glucosamine  [C][S] N-Acetylneuraminate  [R][S][L] 0.71
Y NAG 1471 A, N-acetyl-d-glucosamine  [C][S] N-Acetylneuraminate  [R][S][L] 0.71
N NAG 1472 A, N-acetyl-d-glucosamine  [C][S] N-Acetylneuraminate  [R][S][L] 0.71
N NAG 1473 A, N-acetyl-d-glucosamine  [C][S] N-Acetylneuraminate  [R][S][L] 0.71
N BMA 1476 A, Beta-d-mannose  [C][S]
N MAN 1477 A, Alpha-d-mannose  [C][S]
N MAN 1478 A, Alpha-d-mannose  [C][S]
N BMA 1479 A, Beta-d-mannose  [C][S]
N CA 1483 A, Calcium ion  [C][S]


This page was generated for a tetrameric assembly, no other alternative quaternary structural assemblies exist.