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1qf0

Structure Title:  Thermolysin (e.c.3.4.24.27) complexed with (2-sulphanyl-3-phenylpropanoyl)-phe-tyr. parameters for zn-bidentation of mercaptoacyldipeptides in metalloendopeptidase
Structure Header:  Hydrolase
Associated ECs:  3.4.24.27 [S]

Chains:
Code   Molecule
1.   A   Protein (thermolysin),  current chain [S]

Change domain classification: CATH | SCOP | Pfam


Domain Family Family Name Ligand
bound by
> 1 domain
PDB Ligand (code residue chain, name) Cognate Ligand Similarity
1. Peptidase_M4 [S] Thermolysin metallopeptidase, catalytic domain Y TI2 317 -, (2-sulfanyl-3-phenylpropanoyl)-phe-tyr  [C][S]
Y ZN 320 A, Zinc ion  [C][S] Zinc  [R][S][L] 1
N CA 323 A, Calcium ion  [C][S] Calcium  [R][S][L] 1
Y DMS 325 -, Dimethyl sulfoxide  [C][S]
2. Peptidase_M4_C [S] Thermolysin metallopeptidase, alpha-helical domain Y TI2 317 -, (2-sulfanyl-3-phenylpropanoyl)-phe-tyr  [C][S]
Y ZN 320 A, Zinc ion  [C][S] Zinc  [R][S][L] 1
N CA 321 A, Calcium ion  [C][S] Calcium  [R][S][L] 1
N CA 322 A, Calcium ion  [C][S] Calcium  [R][S][L] 1
N CA 324 A, Calcium ion  [C][S] Calcium  [R][S][L] 1
Y DMS 325 -, Dimethyl sulfoxide  [C][S]
N DMS 326 -, Dimethyl sulfoxide  [C][S]


This page was generated for a monomeric assembly, no other alternative quaternary structural assemblies exist.