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1mf8

Structure Title:  Crystal structure of human calcineurin complexed with cyclosporin a and human cyclophilin
Structure Header:  Hydrolase, ligase
Associated ECs:  3.1.3.16 [S],  5.2.1.8 [S]

Chains:
Code   Molecule
1.   A   Calmodulin-dependent calcineurin a subunit, alpha isoform,  current chain [S]
2. B   Calcineurin b subunit isoform 1
3. C   Cyclophilin a
4. D   Cyclosporin a

Change domain classification: CATH | SCOP | Pfam


Domain Family Family Name Ligand
bound by
> 1 domain
PDB Ligand (code residue chain, name) Cognate Ligand Similarity
1. Metallophos [S] Calcineurin-like phosphoesterase


This page was generated for a tetrameric assembly, no other alternative quaternary structural assemblies exist.