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1ivd

Structure Title:  Structures of aromatic inhibitors of influenza virus neuraminidase
Structure Header:  Hydrolase (o-glycosyl)
Associated ECs:  3.2.1.18 [S]

Chains:
Code   Molecule
1. A   Influenza a subtype n2 neuraminidase
2.   A   Influenza a subtype n2 neuraminidase,  current chain [S]
3. B   Influenza a subtype n2 neuraminidase
4. B   Influenza a subtype n2 neuraminidase

Change domain classification: CATH | SCOP | Pfam


Domain Family Family Name Ligand
bound by
> 1 domain
PDB Ligand (code residue chain, name) Cognate Ligand Similarity
1. Neur [S] Neuraminidase N CA 470 A, Calcium ion  [C][S]
N ST1 471 A, 4-(acetylamino)-3-hydroxy-5-nitrobenzoic acid  [C][S]
N NAG 472 A, N-acetyl-d-glucosamine  [C][S] N-Acetylneuraminate  [R][S][L] 0.71
Y FUL 477 A, Beta-l-fucose  [C][S] N-Acetylneuraminate  [R][S][L] 0.52
Y FUC 477 B, Alpha-l-fucose  [C][S] N-Acetylneuraminate  [R][S][L] 0.52
Y NAG 478 A, N-acetyl-d-glucosamine  [C][S] N-Acetylneuraminate  [R][S][L] 0.71
Y NAG 478 B, N-acetyl-d-glucosamine  [C][S] N-Acetylneuraminate  [R][S][L] 0.71
N MAN 483 B, Alpha-d-mannose  [C][S]
N NAG 484 A, N-acetyl-d-glucosamine  [C][S] N-Acetylneuraminate  [R][S][L] 0.71


This page was generated for a tetrameric assembly, no other alternative quaternary structural assemblies exist.