Figure 6. (a) Stereoscopic view of the electron density of a representative groove, showing the hydration spine. All 16
crystallographically independent grooves have similar hydration spines. For clarity, the electron density is shown
only for the water molecules (small red spheres). Hydrogen bonds are indicated by broken lines. (b) A stereoscopic
view of hydration within the grooves: the distribution of water molecules around the averaged guanine:guanine base
pair. (c) A stereoscopic view of the distribution of water molecules around the 28 observed thymine bases.
The above figure is reprinted
by permission from Elsevier:
J Mol Biol