Figure 3 - full size


Figure 3.
Figure 3. A stereo representation of the active site of MurA with a cross-section through the molecular surface of the enzyme (white dots) showing surface complementarity between the ligands and the protein (stick representation). UDP-GlcNAc and fosfomycin are represented as van der Waals spheres. Atoms are depicted in standard colours. Only residues mentioned in the text are shown, along with water molecules (represented as red crosses) trapped in the catalytic pocket. Figure was produced with the program QUANTA (Molecular Simulations Inc.).

The above figure is reprinted by permission from Cell Press: Structure (1996, 4, 1465-1474) copyright 1996.