Figure 1 - full size

 

Figure 1.
ig. 1. Active site of E. coli alkalinephosphatase. Shown are n,, Zn2, phosphate (Pi),and side-chain ligands. The side chain of Asp-51, which bridges the Mg nd Zn2 sites, is lso shown here; for clarity, the other ligands o Mg are not shown. Zn, interacts with an im- idazole nitrogen of is-412 and His-33, one of he phosphate oxygens, and thearboxylate oxygens of Asp-327. Zn,is oordinated to Asp- His-370, hosphate, and Also shown s Ser-102, which s during the reaction, and which interacts with thephosphate.

The above figure is reprinted from an Open Access publication published by the Protein Society: Protein Sci (1995, 4, 1498-1506) copyright 1995.