Figure 3 - full size

 

Figure 3.
Figure 3. Structure of TF in Complex with Ribosomal Protein S7
(A) Ribbon diagram of tmTF colored by domains. The N-terminal domain (NTD) is colored blue; the PPIase domain green; the C-terminal domain (CTD) red. NTD and PPIase are connected via a linker colored yellow here and subsequently colored red as part of CTD. Disordered TF residues shown as a blue dotted line correspond to the ribosome-binding loop. Orientation is a view down the diad axis of the TF:S7 complex.
(B) Ribbon diagram of TF colored by domains as in (A) except for linker, now red. The yellow ribbon corresponds to tmS7 as it is bound inside the CTD cleft. Orientation has the diad axis vertical.
(C) TF:S7 complex. Two TF molecules (ribbons colored by domains as in B encapsulate two S7 molecules (yellow molecular surfaces). Orientation is as rotated 90° from (B) and as in (A) but rotated by vert, similar 30° about the diad axis. Scale is as in (B).
(D) Surface representation of the TF:S7 complex; TF is colored red and blue; S7 is colored yellow.
(E) Ribbon diagram of substrate-free tmTF colored by domains as in (B). The CTD is superimposed onto that of tmTF in the complex as oriented in (B). The yellow ribbon represents a symmetry-related tmTF with its NTD (solid) bound inside the CTD cleft.
(F) Ribbon diagram of substrate-free ecTF colored by domains as in (B). The core of CTD is superimposed onto that of tmTF as oriented in (B) and (E). The yellow ribbon represents a symmetry-related ecTF with its NTD (solid) bound inside the CTD cleft.

The above figure is reprinted by permission from Cell Press: Cell (2009, 138, 923-934) copyright 2009.