Figure 1 - full size

 

Figure 1.
The fungal FAS multienzyme. (A) Cryo-EM reconstruction of S. cerevisiae FAS contoured at 1.7 σ. One single α- and one single β-chain are colored according to the attached domain representation. Expansion segments in between domains are colored white for the α-chain and pale yellow for the β-chain. (B) The central FAS α-wheel with six bound CER molecules is highlighted in red. Domains are colored according to A, and three docked ACP domains are represented by transparent surfaces.