The fungal FAS multienzyme. (A) Cryo-EM reconstruction of S.
cerevisiae FAS contoured at 1.7 σ. One single α- and one
single β-chain are colored according to the attached domain
representation. Expansion segments in between domains are
colored white for the α-chain and pale yellow for the β-chain.
(B) The central FAS α-wheel with six bound CER molecules is
highlighted in red. Domains are colored according to A, and
three docked ACP domains are represented by transparent surfaces.