Figure 3 - full size

 

Figure 3.
Figure 3. The N-terminus of the helix moves toward the center of the protein, with the main chain atoms from W59 and A60 of the mutant moving by 1.28-1.74 Å (dotted lines). (Inset) The C[ ]trace of the E60A mutant (cyan) is shown against the surface rendering of wild-type FKBP12 (purple), which is partially cut away to reveal the protein core.

The above figure is reprinted by permission from John Wiley & Sons, Inc.: Proteins (2008, 74, 603-611) copyright 2008.