Figure 2. A Model of the Cytoplasmic 80S Ribosome
model of the canine ribosome is shown within a density map of
the ribosome-channel complex. The E site tRNA is shown in red
between the small (ssu) and large subunits (lsu) of the
ribosome. This specimen contained part of the ER translocon (in
magenta) that is composed of Sec61 and TRAP. The latter has a
prominent lumenal domain (LD).
(B) A molecular model of the
canine ribosome is shown in a front view. The subunit rRNAs and
conserved proteins are color coded (see boxes). Novel proteins
(spheres and rods) and expansion segments (red helices) are also
(C) The model of a canine ribosome is shown in a
reverse view within the electron microscopy (EM) density map.
The position of the ER membrane is indicated by dashed lines.
(D) The molecular model of the canine ribosome is shown in
a reverse view.
The above figure is reprinted
from an Open Access publication published by Cell Press: