Figure 2 - full size

 

Figure 2.
Figure 2. A Model of the Cytoplasmic 80S Ribosome
(A) A model of the canine ribosome is shown within a density map of the ribosome-channel complex. The E site tRNA is shown in red between the small (ssu) and large subunits (lsu) of the ribosome. This specimen contained part of the ER translocon (in magenta) that is composed of Sec61 and TRAP. The latter has a prominent lumenal domain (LD).
(B) A molecular model of the canine ribosome is shown in a front view. The subunit rRNAs and conserved proteins are color coded (see boxes). Novel proteins (spheres and rods) and expansion segments (red helices) are also included.
(C) The model of a canine ribosome is shown in a reverse view within the electron microscopy (EM) density map. The position of the ER membrane is indicated by dashed lines.
(D) The molecular model of the canine ribosome is shown in a reverse view.

The above figure is reprinted from an Open Access publication published by Cell Press: Structure (2008, 16, 535-548) copyright 2008.