Figure 6 - full size

 

Figure 6.
Figure 6. Active site of HpDdl in stereoview. A: Superposition of some 3[10]-helix and mutated residues in HpDdl (cyan) and their counterparts (green), ADP and the phosphorylated phosphinate (magenta) in EcDdlB.[20] Ligands and residues are labeled. The secondary structures near the residues are also shown in cartoon model. B: The hydrophobic environment (yellow) around Leu308 in HpDdl. Phosphinate (magenta) and residues are labeled. The secondary structure of the 3[10]-helix is also shown in cartoon model.

The above figure is reprinted by permission from John Wiley & Sons, Inc.: Proteins (2008, 72, 1148-1160) copyright 2008.