Figure 5. Overall structure of HpDdl in stereoview. (A) Three
domains of HpDdl monomer are colored in green, yellow and red
(from N to C-terminus), respectively. The 3-helix is colored
in cyan and the location of putative active site is labeled by
the arrow. (B) The 3-helix (sticks) embedded in 2F[o] - F[c]
type electron density map contoured at 1.0 (blue).
Carbon, oxygen and nitrogen are colored cyan, red and blue
respectively. Residues in the 3-helix are labeled. (C)
Structure comparison after superposition with the C-terminal
domains of HpDdl (cyan), EcDdlB (green, PDB code 2DLN) and
ThcDdl (magenta, PDB code 2FB9). The -loop
and 3-helix regions of HpDdl are indicated.
The above figure is reprinted
by permission from John Wiley & Sons, Inc.: