Figure 4 - full size

 

Figure 4.
FIGURE 4. Conformations of the loops at the entrance to the active site. The loops in GlcCerase occur in a number of conformations, but only two are shown for clarity, in yellow and green; these conformations give the most pronounced changes in the entrance to the active site. Tyr-313, which may play a role in the catalytic mechanism, is indicated. The catalytic residues are shown as red sticks.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2007, 282, 29052-0) copyright 2007.