Figure 6 - full size

 

Figure 6.
Figure 6 Putative membrane binding sites in crystal structures of GlcCerase. Catalytic residues are shown in red and loops 1-3 in green. Substrate binding was modelled according to Dvir et al. (2003[Dvir, H., Harel, M., McCarthy, A. A., Toker, L., Silman, I., Futerman, A. H. & Sussman, J. L. (2003). EMBO Rep. 4, 704-709.]) and shown in yellow. (a) Some of the sulfates are shown in space-filling representation in red. (b) Side-on view [rotated 90° around the horizontal axis relative to (a)] of a putative mode of binding of GlcCerase to negatively charged phospholipids.

The above figure is reprinted by permission from the IUCr: Acta Crystallogr D Biol Crystallogr (2006, 62, 1458-1465) copyright 2006.