Figure 6 Putative membrane binding sites in crystal structures
of GlcCerase. Catalytic residues are shown in red and loops 1-3
in green. Substrate binding was modelled according to Dvir et
al. (2003[Dvir, H., Harel, M., McCarthy, A. A., Toker, L.,
Silman, I., Futerman, A. H. & Sussman, J. L. (2003). EMBO Rep.
4, 704-709.]) and shown in yellow. (a) Some of the sulfates are
shown in space-filling representation in red. (b) Side-on view
around the horizontal axis relative to (a)] of a putative mode
of binding of GlcCerase to negatively charged phospholipids.
The above figure is reprinted
by permission from the IUCr:
Acta Crystallogr D Biol Crystallogr