Figure 5 - full size


Figure 5.
Fig. 5. Dynamic nature of the 14-3-3 dimers. (A) Crystal structure of the apo- isoform looking down the peptide binding grooves, which are labeled open and closed for the individual monomers. (B) Superimposition of all seven closed state 14-3-3 isoforms using only one monomer as the reference, with shown in blue and in green. The other 14-3-3 monomers, which have intermediate positions, are colored transparent gray.