Figure 3 - full size

 

Figure 3.
Figure 3 Active site. (a) The difference electron-density map for DSP18 was generated with the final model, omitting the bound HEPES. The stereo map contoured at the 3.0 level was presented as superposed with the refined model. The hydrogen-bonding interactions around the active site are represented by dashed lines. (b) Electrostatic potential surfaces of DSP18 and VHR (PDB code [183]1vhr ) are presented. Positive and negative potentials are coloured blue and red, respectively. Residues near the active site are labelled.

The above figure is reprinted by permission from the IUCr: Acta Crystallogr D Biol Crystallogr (2006, 62, 582-588) copyright 2006.