Figure 4 Stereo view of the substituted aldamine in the active
site of GadB 1–14.
The C-terminal residues 463–466, the PLP-cofactor and Lys276
appear as sticks (orange and atom colours, while other residues
are in white and atom colours) with the corresponding
2mF[o]-DF[c] electron density (1 ).
Both the epsilon
-nitrogen of Lys276 and the distal side chain nitrogen of His465
form a covalent bond with the C4' atom (hybridized sp^3) of the
The above figure is reprinted
by permission from Macmillan Publishers Ltd: