Figure 4 - full size


Figure 4.
Figure 4 Stereo view of the substituted aldamine in the active site of GadB 1–14. The C-terminal residues 463–466, the PLP-cofactor and Lys276 appear as sticks (orange and atom colours, while other residues are in white and atom colours) with the corresponding 2mF[o]-DF[c] electron density (1 ). Both the epsilon -nitrogen of Lys276 and the distal side chain nitrogen of His465 form a covalent bond with the C4' atom (hybridized sp^3) of the PLP-cofactor.

The above figure is reprinted by permission from Macmillan Publishers Ltd: EMBO J (2006, 25, 2643-2651) copyright 2006.