Figure 4 - full size


Figure 4.
Fig. 4. Direct and water-mediated interactions between MutM and the DNA backbone in the control LRC CC2 (A) and interrogation complexes IC1 (B) and IC2 (C). Dashed lines indicate hydrogen bonding interactions among backbone phosphates in DNA, ordered waters (red spheres), and residues in MutM. The side chains of amino acid residues are shown in green with the numbers colored according to which moiety on the amino acid is involved in the contact: green, side chain; blue, backbone amide NH; red, backbone amide carbonyl; gray, no contact in that particular complex.

The above figure is reprinted by permission from the AAAs: Science (2006, 311, 1153-1157) copyright 2006.