Figure 5 - full size


Figure 5.
Figure 5 Kinetic response to ATP binding of wild-type MutS and E38 mutants. (A) Magnitude of burst amplitude of ADP formation during the first hydrolytic turnover in a rapid quench ATPase assay in the absence and presence of DNA containing a G.T mismatch. (B) Kinetics of ATP-induced MutS release from mismatched (mm) DNA with a free end and (C) from double end-blocked mismatched DNA determined by SPR.

The above figure is reprinted by permission from Macmillan Publishers Ltd: EMBO J (2006, 25, 409-419) copyright 2006.