Stereo images of the active site structures. A, the
accessible thiocyanate-bound active site of Rv3588c. Bubbles
indicate the salt link between Asp-53 and Arg-55. B, comparison
of the accessible (dark gray) and blocked (light gray) sites.
Note in particular the shift of Asp-53 and the drastic changes
of Ser-54 and Val-56.
The above figure is reprinted
by permission from the ASBMB:
J Biol Chem