Figure 1 - full size

 

Figure 1.
Figure 1 (a) and (b) Orthogonal views of the M. viridifaciens sialidase. The catalytic domain (47-403) is in light brown with Neu5Ac2en bound in the active site, the immunoglobulin-like domain (403-505) is in green and the CBM (505-647) is in cyan with lactose bound. The metal ion is shown as a magenta ball. The disulfide between 351-405 linking the first two domains is also shown. (c) Molecular surface coloured according to electrostatic potential; same view as in (a).

The above figure is reprinted by permission from the IUCr: Acta Crystallogr D Biol Crystallogr (2005, 61, 1483-1491) copyright 2005.