Figure 4 - full size

 

Figure 4.
Figure 4. Surface charge distribution of RanBD2 and interaction with peptides. (a) Surface charge distribution in RanBD2. The molecule is shown in the same orientation as in Figure 3(a). (b) Same as (a) after a z-rotation of 90°. The basic patch supposed to bind the DEDDDL motif can be seen in the center. (c) Putative interaction sites of the DEDDDL-peptide mapped on the RanBD2 surface. The molecule is shown in the same orientation as in (a). Residues showing a chemical shift change larger than the mean value plus one half standard deviation, one standard deviation and two standard deviations for a twofold molar excess of the peptide are colored yellow, orange and red, respectively. (d) Same as (c) after a z-rotation of 90°.

The above figure is reprinted by permission from Elsevier: J Mol Biol (2005, 348, 711-725) copyright 2005.