Figure 2 - full size


Figure 2.
Figure 2 (a) The mismatched wobble base pair G304-BrU105 with hydrogen bonding between the N1 and the O6 of the guanine with the O2 and the N3 of the bromouracil, respectively; (b) the mismatched base pair G104-T206* showing similar interactions; (c) in a T*A*T triplet, A403 makes Watson-Crick interactions with T102* and Hoogsten interactions with T101*; (d) [174][pi] -stacking of BrU305 to the phenoxazone ring of actinomycin molecule 1 (* indicates symmetry equivalent).

The above figure is reprinted by permission from the IUCr: Acta Crystallogr D Biol Crystallogr (2005, 61, 407-415) copyright 2005.