Fig. 3. The active site of cobalt(II)-substituted carbonic anhydrase at pit 6.0. Difference electron maps were calculated after refinement of native
coordinates without waters 263, 338 and 339. Positive (continuous lines) and negative (broken lines) IFol - IFcI contours were drawn at +3e.
The occupancy of the sulfate was refined to 0.6.
The above figure is reprinted
by permission from the IUCr:
Acta Crystallogr D Biol Crystallogr