Figure 4 - full size

 

Figure 4.
Figure 4. A schematic diagram of the secondary struc- ture of human CyP A. N and C represent te 1v- and C: termini, respectively. Helices are shown as cylinders and b-strands as arrows. The B-barrel as dimensions of about 14 A for height, and 15 and 17 A for the minor and major xes of the elliptical cross ection of the barrel. Helices: strands an turns are 21%, 36% and 10% of the total amino acid residues, respectively. The hydrophobic core of he barrel is closed by helices H2 and H4 so that ligands are predicted to bind at the surfaces of the barrel.

The above figure is reprinted by permission from Elsevier: J Mol Biol (1992, 228, 539-550) copyright 1992.