Figure 1 - full size

 

Figure 1.
Figure 1 Stereoimages illustrating the mode of binding of the SCN ion to TLN and the rearrangement of the subsite S1-S2. (a) Partial structure of the active site of TLN crystallized in the presence of DMSO/CsCl. (b) Partial structure of the same active site of TLN crystallized in the presence of KSCN. Tyr157 rotates about the [1] angle toward Asp150. The SCN ion tightly binds His231, Glu166 and a water molecule (VMD; Humphrey et al., 1996[Humphrey, W., Dalke, A. & Schulten, K. (1996). J. Mol. Graph. 14, 33-38, 27-28.]).

The above figure is reprinted by permission from the IUCr: Acta Crystallogr D Biol Crystallogr (2002, 58, 2198-2200) copyright 2002.