Figure 4 - full size

 

Figure 4.
Figure 4. Electron Densities for the Bound Inhibitor BOP(A) Model-unbiased, sigmaA-weighted Fo-Fc map of BOP bound to LmGPDH contoured at 2.4 σ (pink) and the anomalous difference Fourier map (red) contoured at 10 σ superimposed with the final model of BOP.(B) The anomalous difference Fourier map (red) contoured at 10 σ for the whole protein region drawn with the C^α model of the LmGPDH and inhibitor BOP. Carbon, nitrogen, oxygen, and bromine are colored brown, blue, red, and pink, respectively.

The above figure is reprinted by permission from Cell Press: Chem Biol (2002, 9, 1189-1197) copyright 2002.