Figure 2 - full size

 

Figure 2.
Figure 2. Electron Densities of the Bound Inhibitor BCP(A) Model-unbiased, sigmaA-weighted Fo-Fc map contoured at 3 σ (light brown), 5 σ (violet), and 7 σ (red) with conformation A of BCP.(B and C) Two alternative conformations (conformation A, green; conformation B, red) of BCP bound to L. mexicana GPDH in a model-unbiased, sigmaA-weighted Fo-Fc map (B) contoured at 3.5 σ (light brown) and an anomalous difference Fourier map contoured at 4.5 σ (red) and (C) an anomalous difference Fourier map contoured at 5.5 σ (red). Carbon, nitrogen, chlorine, and bromine are colored brown, blue, yellow, and pink, respectively. Drawn using MOLSCRIPT [45] and Raster3D [46].

The above figure is reprinted by permission from Cell Press: Chem Biol (2002, 9, 1189-1197) copyright 2002.