Figure 8 - full size

 

Figure 8.
Figure 8. Superposition of the lowest-energy solution structure of TF[PPIase] (blue) and the X-ray structure of FKBP (red). For FKBP the N terminus (residues 1-15) is omitted for clarity. Coordinates for FKBP were taken from the FKBP-FK506 complex, PDB entry 1FKF. The structures were superimposed using residues marked by asterisks in Figure 6, resulting in an rmsd value of 1.3 Å.

The above figure is reprinted by permission from Elsevier: J Mol Biol (2002, 318, 1097-1115) copyright 2002.