Figure 5 - full size


Figure 5.
Fig. 5. The antigen-binding site of cAb-CA05. The cAb-CA05 is shown with the scaffold atoms in gray, CDR1 atoms in blue, CDR2 atoms in green. The CDR3 atoms that interact with the antigen are in red for hydrogen bonding, orange for van der Waals contacts, and black for salt bridge. The Kabat numbering of the amino acids to which the contacting atoms belong is given for reference. The carbonic anhydrase epitope segments 1 (pink dots) and 2 (red dots) are in ball-and-stick representation.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2001, 276, 26285-26290) copyright 2001.