Figure 2 - full size


Figure 2.
Figure 2. Orthogonal views of IFN-gSC1. Ribbon diagrams are shown (a) perpendicular to and (b) parallel with the IFN-gSC1 molecular 2-fold axis. Amino acid residues 1-121 are colored cyan and residues 123-242 are gold. The linker and Asp111 are shown in red. Residues 243-252 were not observed in the electron density. The IFN-gRa binding domain, domain 1, is comprised of helices A, B, C, D, E2, and F2. Receptor binding is prevented in domain 2. It is formed from helices A2, B2, C2, D2, E, and F.

The above figure is reprinted by permission from Elsevier: J Mol Biol (2000, 299, 169-179) copyright 2000.