Figure 4 - full size


Figure 4.
Fig. 4. Schematic representation of compound 5 in the active site pocket of PTP1B. Distances are in Å for noncovalent interactions between PTP1B and compound 5. Van der Waals interactions are illustrated by arcs. Nomenclature used for the different groups of compound 5.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2000, 275, 10300-10307) copyright 2000.