Figure 5 - full size

 

Figure 5.
Figure 5. Representation of the Binding Groove of Δ50Tom20 and the Bound Presequence Peptide(A) Molecular surface of Δ50Tom20 (residues 57–124). Hydrophobic residues comprising the hydrophobic patch (Phe^70, Leu^71, Ile^74, Leu^106, Val^109, Leu^110, Thr^113), and Gln (Gln^67, Gln^75, Gln^102, Gln^104, Gln^105, Gln^108, Gln^111, and Gln^112) and Glu (Glu^78 and Glu^79) in the peripheral region are colored in yellow, orange, and red, respectively. The bound peptide is drawn as a tube with sidechains in magenta for Leu, blue for Arg, and cyan for others. N' and C' denote the N and C termini of the peptide, respectively.(B) Same structure viewed from an angle along the arrow shown in (A).

The above figure is reprinted by permission from Cell Press: Cell (2000, 100, 551-560) copyright 2000.