Figure 7 - full size


Figure 7.
Figure 7. The Bending Model of Spectrin FlexibilityThe lower panel is a hypothetical 20 repeat molecule based on the 2U structures and representing the fully extended conformation. The middle panel depicts an vert, similar 30% decrease in the end-to-end distance of spectrin due to its supercoiling into 2.5 superhelical turns with eight spectrin repeats per turn. The upper panel depicts a further decrease to 50% of the initial end-to-end distance by a further decrease in the pitch of the superhelix.

The above figure is reprinted by permission from Cell Press: Cell (1999, 98, 523-535) copyright 1999.