Figure 4 - full size


Figure 4.
Fig. 4. Superposition of the CPS allosteric binding pockets with bound IMP or glutamine/inorganic phosphate. The model described in this report is shown in black, whereas the structure of CPS complexed with glutamine and inorganic phosphate, as described by Thoden et al. (2), is displayed in red. Note the nearly exact correspondence between the inorganic phosphate and the phosphoryl moiety of the nucleotide.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (1999, 274, 22502-22507) copyright 1999.