Figure 9. FIG. 9. The proposed reaction mechanism of ThrS with the substrate, HSerP. A, Michaelis complex; B, external aldimine; C, carbanion intermediate; D, ketimine; E, enamine; F, , -unsaturated ketimine; G, , -unsaturated aldimine; H, external aldimine between PLP and threonine.
The above figure is reprinted by permission from the ASBMB: J Biol Chem (2003, 278, 46035-46045) copyright 2003.