Figure 8 - full size

 

Figure 8.
Figure 8. The ensemble of 50 final structures. (a) C^αtrace of all residues; (b) side-chains forming the hydrophobic core around Trp99; (c) Overlay of the 50 NMR structure (in grey) and the X-ray crystal structure [Hyvonen et al 1995]. The residues involved in IP3 binding are shown.

The above figure is reprinted by permission from Elsevier: J Mol Biol (1997, 269, 408-422) copyright 1997.